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To achieve ideal weight, a lot of people who depend their life on a diet that manifold. But recently, a study from the United States have identified another potential of a special diet called the ketogenic diet as delay the aging process.
The team of researchers from the Gladstone Institute suggests that a diet that emphasizes low-calorie diet and carbohydrates that can trigger the production of a compound that plays an important role in delaying the aging process.
If the concentration is low, a compound called beta-hydroxybutyrate (beta-OHB) or 'ketone body' can help protect body cells from oxidative stress that contributes to the aging process.
Oxidative stress occurs when the body's cells use oxygen to produce energy but besides that this activity also resulted in the release of other toxic molecules known as free radicals.
The problem is when the age, the body's cells are no longer effective in clearing these molecules free radicals causing cell damage, oxidative stress and the effects of aging. But the researchers found that beta-OHB was really able to help delay the process.
"We found that beta-OHB, one of the body's main source of energy when exercising or fasting, can inhibit the formation of enzymes that promote the emergence of 'oxidative stress' and protects cells from aging," said researcher Eric Verdin zeenews quoted as saying on Monday (10.12.2012).
These findings obtained by the research team after passing a series of experiments involving a number of participants were asked to chronic calorie restriction diet. From there it was seen that calorie restriction triggers the production of beta-OHB that can inhibit the activity of a group of enzymes called histone deacetylase, or HDAC.
Investigate a calibaration, apparently normal existence HDAC this 'work' deadly pair of genes called Foxo3a and MT2. But with increased levels of beta-OHB, these compounds can inhibit HDAC doing it or in other words a pair of genes had finally become active. Whereas once activated, they can start an activity to help the body's cells against oxidative stress siege.
"This breakthrough also expand our understanding of the mechanisms behind long known HDAC involvement in aging and neurological diseases such as Alzheimer's, Parkinson's, autism and traumatic brain injury disease that has had few treatment alternatives," said another researcher, Katerina Akassoglou.
The study has been published in the journal Science.
The team of researchers from the Gladstone Institute suggests that a diet that emphasizes low-calorie diet and carbohydrates that can trigger the production of a compound that plays an important role in delaying the aging process.
If the concentration is low, a compound called beta-hydroxybutyrate (beta-OHB) or 'ketone body' can help protect body cells from oxidative stress that contributes to the aging process.
Oxidative stress occurs when the body's cells use oxygen to produce energy but besides that this activity also resulted in the release of other toxic molecules known as free radicals.
The problem is when the age, the body's cells are no longer effective in clearing these molecules free radicals causing cell damage, oxidative stress and the effects of aging. But the researchers found that beta-OHB was really able to help delay the process.
"We found that beta-OHB, one of the body's main source of energy when exercising or fasting, can inhibit the formation of enzymes that promote the emergence of 'oxidative stress' and protects cells from aging," said researcher Eric Verdin zeenews quoted as saying on Monday (10.12.2012).
These findings obtained by the research team after passing a series of experiments involving a number of participants were asked to chronic calorie restriction diet. From there it was seen that calorie restriction triggers the production of beta-OHB that can inhibit the activity of a group of enzymes called histone deacetylase, or HDAC.
Investigate a calibaration, apparently normal existence HDAC this 'work' deadly pair of genes called Foxo3a and MT2. But with increased levels of beta-OHB, these compounds can inhibit HDAC doing it or in other words a pair of genes had finally become active. Whereas once activated, they can start an activity to help the body's cells against oxidative stress siege.
"This breakthrough also expand our understanding of the mechanisms behind long known HDAC involvement in aging and neurological diseases such as Alzheimer's, Parkinson's, autism and traumatic brain injury disease that has had few treatment alternatives," said another researcher, Katerina Akassoglou.
The study has been published in the journal Science.
Source: Zeenews
